Elaine C Wirrell Selected Research

Lennox Gastaut Syndrome

1/2022	New and emerging pharmacologic treatments for developmental and epileptic encephalopathies.
1/2021	The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results.
5/2018	Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.

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Elaine C Wirrell Research Topics

Disease

32	Epilepsy (Aura) 03/2024 - 03/2002
29	Seizures (Absence Seizure) 03/2024 - 01/2002
14	Myoclonic Epilepsies (Myoclonic Encephalopathy) 03/2024 - 06/2006
8	Brain Diseases (Brain Disorder) 01/2023 - 06/2006
5	Infantile Spasms (West Syndrome) 01/2022 - 09/2012
4	Status Epilepticus (Complex Partial Status Epilepticus) 01/2019 - 09/2015
4	Epileptic Syndromes 11/2017 - 06/2006
3	Partial Epilepsies (Epilepsy, Partial) 04/2023 - 05/2014
3	Temporal Lobe Epilepsy 01/2023 - 09/2009
3	Tuberous Sclerosis (Bourneville's Disease) 01/2022 - 01/2021
3	Lennox Gastaut Syndrome 01/2022 - 05/2018
3	Spasm (Spasms) 10/2021 - 06/2012
3	Drug Resistant Epilepsy 01/2021 - 05/2012
3	Nervous System Diseases (Neurological Disorders) 01/2018 - 01/2012
2	Weight Gain 07/2022 - 02/2003
2	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2022 - 01/2021
2	Neuroinflammatory Diseases 01/2020 - 12/2016
2	Glioma (Gliomas) 01/2018 - 05/2012
2	Hippocampal Sclerosis 01/2012 - 09/2009
1	Generalized Epilepsy 04/2023
1	Encephalocele (Encephalocele, Frontal) 01/2023
1	Craniocerebral Trauma (Head Injury) 01/2023
1	Obesity 01/2023
1	Weight Loss (Weight Reduction) 07/2022
1	COVID-19 11/2020
1	Channelopathies 01/2019
1	Sleepiness 05/2018
1	Diarrhea 05/2018
1	Body Weight (Weight, Body) 05/2018
1	Infections 12/2016
1	Stiff-Person Syndrome (Stiff Man Syndrome) 11/2014
1	Febrile Seizures (Febrile Seizure) 09/2013

Drug/Important Bio-Agent (IBA)

14	Anticonvulsants (Antiepileptic Drugs)IBA 01/2023 - 05/2008
9	Valproic Acid (Depakote)FDA LinkGeneric 03/2024 - 02/2003
8	stiripentolIBA 03/2024 - 09/2013
6	Clobazam (HR 376)IBA 03/2024 - 06/2016
5	Levetiracetam (Keppra)FDA LinkGeneric 07/2022 - 06/2016
5	CannabidiolIBA 07/2022 - 05/2018
5	FenfluramineIBA 07/2022 - 01/2019
4	Vigabatrin FDA Link 07/2022 - 02/2012
4	Sodium Channels (Sodium Channel)IBA 01/2018 - 06/2006
3	Lamotrigine (Lamictal)FDA LinkGeneric 07/2022 - 06/2016
3	Topiramate (Topamax)FDA LinkGeneric 07/2022 - 02/2012
3	Carbamazepine (Tegretol)FDA LinkGeneric 07/2022 - 07/2010
2	Lacosamide FDA Link 10/2022 - 07/2022
2	brivaracetamIBA 10/2022 - 07/2022
2	Ethosuximide (Zarontin)FDA LinkGeneric 07/2022 - 01/2018
2	Oxcarbazepine (Trileptal)FDA LinkGeneric 07/2022 - 06/2016
2	TOR Serine-Threonine KinasesIBA 01/2022 - 01/2021
2	Antisense OligonucleotidesIBA 01/2022 - 01/2019
2	Adrenocorticotropic Hormone (ACTH)FDA Link 09/2021 - 02/2012
2	SteroidsIBA 09/2021 - 02/2012
2	Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA 01/2018 - 05/2012
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 05/2012
2	Phenobarbital (Luminal)FDA Link 01/2018 - 06/2005
2	Leucine (L-Leucine)FDA Link 01/2018 - 05/2012
2	Immunoglobulin G (IgG)IBA 01/2018 - 11/2014
2	BenzodiazepinesIBA 01/2017 - 06/2005
2	Phenytoin (Dilantin)FDA LinkGeneric 06/2016 - 06/2005
2	Amino Acids FDA Link 04/2015 - 01/2002
2	Lactic Acid (Lactate)FDA LinkGeneric 04/2015 - 01/2002
2	Biomarkers (Surrogate Marker)IBA 11/2014 - 03/2012
2	AutoantibodiesIBA 05/2012 - 03/2012
1	CenobamateIBA 04/2023
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2023
1	TESIBA 01/2023
1	Zonisamide (Zonegran)FDA LinkGeneric 07/2022
1	eslicarbazepineIBA 07/2022
1	rufinamide FDA Link 07/2022
1	Pregabalin (Lyrica)FDA Link 07/2022
1	Felbamate (Felbatol)FDA Link 07/2022
1	perampanelIBA 07/2022
1	Ion Channels (Ion Channel)IBA 01/2022
1	CeroidIBA 01/2022
1	trans-sodium crocetinate (crocetin)IBA 09/2021
1	Everolimus FDA Link 01/2021
1	EnzymesIBA 01/2021
1	palmitoyl-protein thioesteraseIBA 01/2021
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2020
1	SolutionsIBA 05/2018
1	dimemorfan (AT 17)IBA 01/2018
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 12/2016
1	CytokinesIBA 12/2016
1	BromidesIBA 06/2016
1	Acetazolamide (Diamox)FDA LinkGeneric 09/2015
1	AcidsIBA 04/2015
1	1,3-dipropyl-8-phenylxanthineIBA 11/2014

Therapy/Procedure

26	Therapeutics 03/2024 - 06/2005
8	Ketogenic Diet 11/2020 - 03/2002
5	Immunotherapy 01/2018 - 04/2011
2	Precision Medicine 01/2023 - 10/2021
2	Electrodes (Electrode) 10/2014 - 06/2014
2	Hemispherectomy 06/2012 - 11/2010
1	Secondary Prevention 07/2023
1	Deep Brain Stimulation 01/2021
1	Ambulatory Care (Outpatient Care) 11/2020
1	High-Protein Low-Carbohydrate Diet (Atkins Diet) 01/2019
1	Treatment Delay 01/2018
1	Speech Therapy (Therapy, Speech) 06/2016
1	Vagus Nerve Stimulation 06/2016